METHYL 4-CHLORO-6-(HYDROXYMETHYL)PICOLINATE

METHYL 4-CHLORO-6-(HYDROXYMETHYL)PICOLINATE - Names and Identifiers

Name	methyl 4-chloro-6-(hydroxymethyl)picolinate
Synonyms	METHYL 4-CHLORO-6-(HYDROXYMETHYL)PICOLINATE methyl 4-chloro-6-(hydroxymethyl)picolinate 4-Chloro-6-hydroxymethyl-pyridine-2-carboxylic acid methyl ester
CAS	109880-43-5

METHYL 4-CHLORO-6-(HYDROXYMETHYL)PICOLINATE - Physico-chemical Properties

Molecular Formula	C8H8ClNO3
Molar Mass	201.61
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

METHYL 4-CHLORO-6-(HYDROXYMETHYL)PICOLINATE - Introduction

Methyl 4-chloro-6-hydroxymethyl-2-picolinate, also known as CPME, is an organic compound.

Nature:
1. appearance: colorless liquid.
2. molecular formula: C8H8ClNO3.
3. molecular weight: 201.61.
4. melting point:-11 ℃.
5. Boiling point: 108-110 ℃.
6. density: 1.350g/cm³.
7. Solubility: Soluble in organic solvents, insoluble in water.

Use:
1. As an intermediate of organic synthetic chemicals, it can be used to synthesize compounds such as drugs, pesticides and dyes.
2. As a solvent for organic synthesis reactions, it is commonly used in carboxylic acid activation reactions, amine acid activation reactions, etc.

Preparation Method:
There are many methods for preparing methyl 4-chloro-6-hydroxymethyl-2-pyridinecarboxylate. A general method is to react methyl 2-pyridinecarboxylate with chloroformyl chloride, and then hydrolyze with sodium hydroxide to obtain the target product.

Safety Information:
1. 4-Chloro-6-hydroxymethyl-2-picolinic acid methyl ester is a low-toxic compound, but it still needs to be handled carefully to avoid contact with eyes and skin.
2. Use should wear appropriate protective gloves, goggles and protective clothing.
3. If ingested or inhaled by mistake, seek medical attention immediately.

Last Update：2024-04-09 02:00:41